Research
Original data & PubMed-cited science on GLP-1 weight loss.
We track every major GLP-1 telehealth provider in the United States and publish two kinds of long-form pieces: data investigations using our live dataset, and PubMed-cited scientific deep-dives on the studies that actually matter. Both update as the underlying data changes.
- Data investigation9 min · 6 sources
GLP-1 Compounded Pricing Index 2026
We tracked monthly cash prices across the entire telehealth market for compounded semaglutide and tirzepatide. Here's the median, the cheapest decile, and the gap to brand-name Wegovy — updated live as our dataset changes.
- Pricing data
- Compounded GLP-1
- Live dataset
- Scientific deep-dive14 min · 14 sources
Semaglutide and Muscle Mass: What the STEP Trial Sub-Analyses Actually Show
Up to 40% of weight lost on semaglutide is lean mass, not fat. We unpack the STEP-1 DEXA sub-analysis, the sarcopenia debate, and the protein-and-resistance-training protocols that have actually been studied in trials.
- Semaglutide
- Body composition
- PubMed sourced
- Scientific deep-dive13 min · 12 sources
Tirzepatide vs Semaglutide: A Head-to-Head Look at SURMOUNT and STEP
Tirzepatide consistently outperforms semaglutide on weight loss in head-to-head trial comparisons — but the picture is more nuanced when you look at side effects, discontinuation rates, and cost per pound lost. Here's the full data.
- Tirzepatide
- Semaglutide
- PubMed sourced
- Scientific deep-dive11 min · 9 sources
Compounded Semaglutide Bioequivalence: What 503A Pharmacies Actually Have to Test
Is compounded semaglutide actually the same molecule as Wegovy? The answer is more interesting than either side of the debate suggests. We walk through the FDA's compounding rules, the salt-form controversy, and what tests reputable pharmacies actually run.
- Compounded GLP-1
- Pharmacy regulation
- FDA sourced
How we work
Every data point in our investigations is verified directly against provider websites, and the dataset updates continuously. Every scientific deep-dive cites primary literature from PubMed, the FDA, or peer-reviewed clinical trials — never blog summaries or marketing pages. Articles are reviewed and revised whenever the underlying evidence base changes.
We do not sell or recommend specific medical treatments — talk to a licensed clinician before starting any medication. Read our full methodology →