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Strut Health vs Synergy Rx

An in-depth comparison of two leading GLP-1 Providers

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8.1

Strut Health

Best for oral-lozenge compounded GLP-1 access
★★★★4.1

Starting at $99/mo

CompoundedSemaglutideTirzepatideOral Lozenge Option
Visit Strut Health
7.4

Synergy Rx

Best for broadest drug catalog in the Lion MD white-label cluster
★★★3.7

Starting at $199/mo

CompoundedBrandSemaglutideTirzepatide
Visit Synergy Rx

Side-by-Side Comparison

FeatureStrut HealthSynergy Rx
Overall Score8.1/107.4/10
Starting Price$99/mo$199/mo
Editorial Rating4.1 ★ /53.7 ★ /5
Features6 features6 features
States Available490
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

Strut Health

Pros

  • Both LegitScript and ACHC accreditation — pharmacy oversight standard most compounded GLP-1 providers don't advertise
  • Oral lozenge formulation available for semaglutide ($99/mo) and tirzepatide ($199/mo) — injection-free alternative
  • Transparent auto-refill pricing with 13–21% savings vs. one-off orders
  • Free unlimited follow-up messaging with board-certified US physicians
  • 49 states covered (only Arkansas excluded as of September 2024)

Cons

  • 'Medical necessity' eligibility gate — Strut's prescribers evaluate whether treatment is medically appropriate but the criteria are not publicly defined, so users can't self-screen before paying for a consultation
  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
  • Pharmacy partners not publicly named — users can't independently verify 503A/503B compounding source
  • No insurance accepted — cash pay only
  • Phone consultation requirement varies by state (not every state mandates a synchronous visit)

Synergy Rx

Pros

  • Broad drug catalog: compounded sema/tirz in both injection and oral dissolving tablet formats, plus brand-name Ozempic, Wegovy, and Mounjaro
  • Claims 50,000+ patients per homepage as of late 2025
  • All 50 US states subject to state telehealth regulations
  • Same named medical team as Breeze Meds and Care Bare Rx (Dr. Carr and Dr. Tenbrink via Lion MD)
  • Four named 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma Rx)
  • LegitScript seal displayed in footer

Cons

  • Runs on the same Lion MD clinician network and the same 4 compounding pharmacies as Breeze Meds and Care Bare Rx — the three brands are white-labeled storefronts on top of one underlying operation
  • Mandatory individual arbitration + class action waiver in ToS (30-day opt-out window from signup)
  • Consultation fees are non-refundable and all prescription sales are final per ToS
  • Platform explicitly disclaims liability for third-party pharmacy medication quality: 'SynergyRx makes no representations or warranties regarding the efficacy, safety, or outcomes of any medication provided through these third parties'
  • State availability is 'subject to each state's telehealth and prescribing regulations' — the full list of active states requires contacting customer service rather than being published
  • Do NOT confuse with the unrelated 'Synergy Rx Pharmacy' (San Diego, CA) that issued a voluntary nationwide recall in February 2017 for non-sterile compounded products — that is a different entity in a different state
  • Do not visit synergyrx.com — it is a parked domain on Sedo and unrelated to the telehealth brand. The correct domain is synergyrx.co

Our Verdict

Winner: Strut HealthScore: 8.1/10

Strut Health edges out Synergy Rx with a higher overall score of 8.1/10 and is particularly strong for oral-lozenge compounded GLP-1 access. Synergy Rx remains a solid alternative, especially if you're looking for broadest drug catalog in the Lion MD white-label cluster.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.