MyStart Health vs TMates
An in-depth comparison of two leading GLP-1 Providers
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MyStart Health
Best for fastest compounded GLP-1 onboarding with a price lockStarting at $299/mo
TMates
Best for nationwide compounded GLP-1 availability including Puerto RicoStarting at $199/mo
Side-by-Side Comparison
| Feature | MyStart Health | TMates |
|---|---|---|
| Overall Score | ✓7.7/10 | 6.3/10 |
| Starting Price | $299/mo | ✓$199/mo |
| Editorial Rating | ✓3.9 ★ /5 | 3.2 ★ /5 |
| Features | ✓6 features | 4 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
MyStart Health
Pros
- ✓Price Lock Guarantee — base monthly rate ($299) doesn't increase even when your prescribed dose escalates
- ✓Fast onboarding: quoted 5-minute intake, 24-hour prescription turnaround, 2–4 day shipping
- ✓24/7 access to the care team with unlimited clinician messaging included
- ✓LegitScript certified
- ✓Transparent Section 503A compounding disclosure on every landing page
Cons
- ✗Not BBB accredited — BBB rating of C+ with 10 complaints filed against the business (BBB file opened April 24, 2025), most involving shipping delays and customer service access issues in early 2026
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Oral tirzepatide referenced in marketing but FAQ clarifies injectable is 'currently more common' — no FDA-approved oral tirzepatide exists, and the November 2025 Chimicles class action against OpenLoop/Triad Rx over unapproved oral tirzepatide products is a cautionary data point for the category
- ✗Very recent company (incorporated May 21, 2024 per BBB) — limited operational track record
- ✗Pharmacy partners not publicly named — no independent way to verify 503A compliance
- ✗Clinical efficacy claims are based on a homepage survey of only 16 self-reporting customers
TMates
Pros
- ✓All-inclusive monthly pricing covers medication, consultations, nutrition coaching, and 24/7 support with no separate membership fee
- ✓Available in all 50 US states plus Puerto Rico and other US territories
- ✓Both compounded semaglutide and tirzepatide offered
- ✓Fast stated turnaround (intake to medication delivery in 2–3 days)
Cons
- ✗No disclosed third-party accreditations (no verified LegitScript, PCAB, ACHC, or NABP) — weaker pharmacy-oversight signal than competitors
- ✗BBB rating B+ (not accredited) with 8 complaints filed, most involving billing and cancellation friction
- ✗Trustpilot reviews show partial-refund and contact-difficulty reports, and some customer posts allege reviews have been removed
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Pharmacy partners not publicly named — TMates explicitly disclaims both medical practice and pharmacy dispensing responsibility, routing both to independent third parties
- ✗Also sells Schedule III testosterone products and other wellness SKUs alongside GLP-1s — worth knowing about for readers who want a GLP-1-focused provider
Our Verdict
MyStart Health edges out TMates with a higher overall score of 7.7/10 and is particularly strong for fastest compounded GLP-1 onboarding with a price lock. TMates remains a solid alternative, especially if you're looking for nationwide compounded GLP-1 availability including Puerto Rico.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.