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LillyDirect Foundayo vs Midi Health

An in-depth comparison of two leading GLP-1 Providers

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8.5

LillyDirect Foundayo

Best for patients with commercial insurance who want the cheapest legal brand-name GLP-1
★★★★4.3

Starting at $25/mo

Manufacturer DirectFoundayoBrand NameLilly Savings Card
Visit LillyDirect Foundayo
7.0

Midi Health

Best for women in menopause / perimenopause with commercial insurance who want GLP-1 prescribing as part of a broader hormone + metabolic care plan, not as a standalone weight-loss product
★★★3.5

Starting at $128/mo

Menopause SpecialtyCompounded SemaglutideAll 50 StatesCommercial Insurance Accepted
Visit Midi Health

Side-by-Side Comparison

FeatureLillyDirect FoundayoMidi Health
Overall Score8.5/107.0/10
Starting Price$25/mo$128/mo
Editorial Rating4.3 ★ /53.5 ★ /5
Features5 features4 features
States Available510
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

LillyDirect Foundayo

Pros

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Cons

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow

Midi Health

Pros

  • Nationwide availability in all 50 states (verified on the public homepage)
  • Accepts commercial insurance — differentiator vs most cash-pay-only GLP-1 telehealth
  • Menopause + metabolic health specialty framing — useful for women in the demographic where GLP-1 efficacy and weight regulation overlap most
  • Compounded semaglutide pricing starts at $127.90/mo for uninsured patients per the public pricing/insurance page

Cons

  • Does NOT accept Medicare, Medicaid, or Medi-Cal — eliminates roughly 40% of the insured US adult population
  • GLP-1 prescribing is clinician-discretionary inside a broader menopause care plan, NOT a guaranteed offering at intake — readers signing up purely for GLP-1 access may not get it
  • Menopause-focused — not the right fit for men or younger women whose primary need is weight loss

Our Verdict

Winner: LillyDirect FoundayoScore: 8.5/10

LillyDirect Foundayo edges out Midi Health with a higher overall score of 8.5/10 and is particularly strong for patients with commercial insurance who want the cheapest legal brand-name GLP-1. Midi Health remains a solid alternative, especially if you're looking for women in menopause / perimenopause with commercial insurance who want GLP-1 prescribing as part of a broader hormone + metabolic care plan, not as a standalone weight-loss product.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.