Enhance MD vs Sprout Health
An in-depth comparison of two leading GLP-1 Providers
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Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $49/mo
Sprout Health
Best for LegitScript-verified compounded GLP-1 via named pharmaciesStarting at $249/mo
Side-by-Side Comparison
| Feature | Enhance MD | Sprout Health |
|---|---|---|
| Overall Score | ✓8.6/10 | 7.5/10 |
| Starting Price | ✓$49/mo | $249/mo |
| Editorial Rating | ✓4.3 ★ /5 | 3.8 ★ /5 |
| Features | ✓6 features | 4 features |
| States Available | 39 | ✓44 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Enhance MD
Pros
- ✓Baseline and ongoing metabolic lab panels (CMP, lipids, TSH, HbA1c) at Quest Diagnostics every 6 months — a rigor most compounded GLP-1 providers skip entirely
- ✓Mandatory one-on-one video visit with a US-licensed MD or NP before the first prescription — not a pure-async questionnaire model
- ✓Three pricing tiers including a combined semaglutide + tirzepatide Elite plan ($322/mo ongoing) — useful for patients plateaued on a single GLP-1
- ✓LegitScript-certified 503A pharmacy network: Tru Meds Rx, Strive Pharmacy, Pharmacy Hub
- ✓Aggressive first-month intro pricing: $49 on Core, $99 on Advanced, $189 on Elite
- ✓Unlimited clinician messaging and dose-adjustment support included
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
- ✗Not available in 10 states: Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, South Carolina, Tennessee, West Virginia
- ✗Mandatory lab work adds 5–10 days to onboarding vs. async-only competitors
- ✗No insurance accepted — cash pay, HSA/FSA eligible
- ✗First-month intro pricing resets to full tier rate after 30 days — the $49/$99/$189 numbers are not the ongoing cost
Sprout Health
Pros
- ✓LegitScript certification confirmed
- ✓Both compounded semaglutide and tirzepatide available
- ✓44-state coverage via a pre-qualification quiz and licensed clinician review
- ✓Two named 503A pharmacy partners: Foothills Pharmacy and Promise Pharmacy
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Not available in Alabama, Arkansas, California, Louisiana, Mississippi, or North Dakota
- ✗Relatively high base pricing ($249/mo for sema, $299/mo for tirz) compared to intro-priced competitors
- ✗Pharmacy partner accreditation details (PCAB/ACHC) not independently verified
Our Verdict
Enhance MD edges out Sprout Health with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Sprout Health remains a solid alternative, especially if you're looking for LegitScript-verified compounded GLP-1 via named pharmacies.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.