Enhance MD vs MyStart Health
An in-depth comparison of two leading GLP-1 Providers
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Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $49/mo
MyStart Health
Best for fastest compounded GLP-1 onboarding with a price lockStarting at $299/mo
Side-by-Side Comparison
| Feature | Enhance MD | MyStart Health |
|---|---|---|
| Overall Score | ✓8.6/10 | 7.7/10 |
| Starting Price | ✓$49/mo | $299/mo |
| Editorial Rating | ✓4.3 ★ /5 | 3.9 ★ /5 |
| Features | 6 features | 6 features |
| States Available | ✓39 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Enhance MD
Pros
- ✓Baseline and ongoing metabolic lab panels (CMP, lipids, TSH, HbA1c) at Quest Diagnostics every 6 months — a rigor most compounded GLP-1 providers skip entirely
- ✓Mandatory one-on-one video visit with a US-licensed MD or NP before the first prescription — not a pure-async questionnaire model
- ✓Three pricing tiers including a combined semaglutide + tirzepatide Elite plan ($322/mo ongoing) — useful for patients plateaued on a single GLP-1
- ✓LegitScript-certified 503A pharmacy network: Tru Meds Rx, Strive Pharmacy, Pharmacy Hub
- ✓Aggressive first-month intro pricing: $49 on Core, $99 on Advanced, $189 on Elite
- ✓Unlimited clinician messaging and dose-adjustment support included
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
- ✗Not available in 10 states: Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, South Carolina, Tennessee, West Virginia
- ✗Mandatory lab work adds 5–10 days to onboarding vs. async-only competitors
- ✗No insurance accepted — cash pay, HSA/FSA eligible
- ✗First-month intro pricing resets to full tier rate after 30 days — the $49/$99/$189 numbers are not the ongoing cost
MyStart Health
Pros
- ✓Price Lock Guarantee — base monthly rate ($299) doesn't increase even when your prescribed dose escalates
- ✓Fast onboarding: quoted 5-minute intake, 24-hour prescription turnaround, 2–4 day shipping
- ✓24/7 access to the care team with unlimited clinician messaging included
- ✓LegitScript certified
- ✓Transparent Section 503A compounding disclosure on every landing page
Cons
- ✗Not BBB accredited — BBB rating of C+ with 10 complaints filed against the business (BBB file opened April 24, 2025), most involving shipping delays and customer service access issues in early 2026
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Oral tirzepatide referenced in marketing but FAQ clarifies injectable is 'currently more common' — no FDA-approved oral tirzepatide exists, and the November 2025 Chimicles class action against OpenLoop/Triad Rx over unapproved oral tirzepatide products is a cautionary data point for the category
- ✗Very recent company (incorporated May 21, 2024 per BBB) — limited operational track record
- ✗Pharmacy partners not publicly named — no independent way to verify 503A compliance
- ✗Clinical efficacy claims are based on a homepage survey of only 16 self-reporting customers
Our Verdict
Enhance MD edges out MyStart Health with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. MyStart Health remains a solid alternative, especially if you're looking for fastest compounded GLP-1 onboarding with a price lock.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.