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AM Rx vs Wisp

An in-depth comparison of two leading GLP-1 Providers

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5.9

AM Rx

Best for patients with insurance seeking brand-name GLP-1 access (review regulatory warnings carefully)
★★★☆☆3

Starting at $25/mo

Compounded SemaglutideOzempicWegovyZepbound
Visit AM Rx
7.0

Wisp

Best for buyers who want a board-certified telehealth platform offering both branded injectables AND a sublingual alternative — with full disclosure that the sublingual form is not human-tested
★★★3.5

Starting at $225/mo

Brand WegovyBrand ZepboundBrand SaxendaCompounded Sublingual Semaglutide
Visit Wisp

Side-by-Side Comparison

FeatureAM RxWisp
Overall Score5.9/107.0/10
Starting Price$25/mo$225/mo
Editorial Rating3 ★ /53.5 ★ /5
Features6 features6 features
States Available00
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA Warnings2 warningsNone

Pros & Cons

AM Rx

Pros

  • Insurance coordination for brand-name GLP-1s — as low as $25/mo
  • All four major brand-name GLP-1s available (Ozempic, Wegovy, Zepbound, Mounjaro)
  • HSA and FSA accepted
  • Video visits available (not just async) with providers averaging 10+ years experience
  • Compounded semaglutide from $151/mo quarterly

Cons

  • Active FTC/DOJ lawsuit for deceptive billing and subscription practices (ROSCA violations)
  • Two FDA warning letters (Sept 2025, Feb 2026) for misbranding compounded GLP-1 products
  • Novo Nordisk false advertising lawsuit (Aug 2025)
  • Parent entity Zealthy has BBB D- rating with 2,370+ complaints
  • Trustpilot 2.0/5 — 85% one-star reviews citing billing disputes and unreachable support
  • No visible LegitScript certification or PCAB accreditation
  • No named pharmacy partners — compounding source not disclosed
  • No FDA compounding disclaimer on the website
  • State availability not publicly disclosed
  • Founder Kyle Robertson previously ran Cerebral, which settled FTC charges for similar practices
  • Same corporate entity (FitRX LLC) as Zealthy and FitRx — shares regulatory history

Wisp

Pros

  • Wider GLP-1 menu than the prior stub suggested — both branded injectables (Wegovy, Zepbound, Saxenda) AND the compounded sublingual option
  • LegitScript certified, board-certified providers (Dr. Shannon Chatham DO, Andrea Sleeth WHNP-BC publicly named)
  • Wisp's product page uses appropriately cautious language around sublingual: 'lab tests using human-derived tissues suggest it may begin working' and 'effectiveness in patients may vary' — disclosure is more rigorous than most compounded GLP-1 marketing

Cons

  • EFFECTIVENESS CAVEAT: sublingual compounded semaglutide has not been tested in humans — Wisp's own product page explicitly states this. Injectables (Wegovy, Zepbound, Saxenda) on the same platform have FDA safety/efficacy data; sublingual does not.
  • Pharmacy partners not publicly named
  • States served list not publicly enumerated

Our Verdict

Winner: WispScore: 7.0/10

Wisp edges out AM Rx with a higher overall score of 7.0/10 and is particularly strong for buyers who want a board-certified telehealth platform offering both branded injectables AND a sublingual alternative — with full disclosure that the sublingual form is not human-tested. AM Rx remains a solid alternative, especially if you're looking for patients with insurance seeking brand-name GLP-1 access (review regulatory warnings carefully).

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.