Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

Amble vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.4

Amble

Best for mainstream telehealth GLP-1 access
★★★3.7

Starting at $179/mo

CompoundedSemaglutideTirzepatide
Visit Amble
7.8

NewSelf

Best for lowest-cost compounded GLP-1 with pharmacy quality transparency
★★★3.9

Starting at $100/mo

Compounded SemaglutideCompounded TirzepatideB12 + Glycine EnhancedLegitScript Verified
Visit NewSelf

Side-by-Side Comparison

FeatureAmbleNewSelf
Overall Score7.4/107.8/10
Starting Price$179/mo$100/mo
Editorial Rating3.7 ★ /53.9 ★ /5
Features3 features5 features
States Available5049
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

Amble

Pros

  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Cons

  • Limited public information on program details

NewSelf

Pros

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Cons

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelfScore: 7.8/10

NewSelf edges out Amble with a higher overall score of 7.8/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Amble remains a solid alternative, especially if you're looking for mainstream telehealth GLP-1 access.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.