Actin vs Vyora Wellness
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
Vyora Wellness
Best for patients wanting coaching-inclusive compounded GLP-1 programsStarting at $299/mo
Side-by-Side Comparison
| Feature | Actin | Vyora Wellness |
|---|---|---|
| Overall Score | 7.0/10 | 7.0/10 |
| Starting Price | ✓$133/mo | $299/mo |
| Editorial Rating | 3.5 ★ /5 | 3.5 ★ /5 |
| Features | 2 features | ✓4 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
Vyora Wellness
Pros
- ✓LegitScript certified
- ✓Price includes nutritional guidance, 24/7 coaching, and community access
- ✓Both semaglutide and tirzepatide available
- ✓BMI 25+ eligibility threshold (lower than some competitors)
Cons
- ✗State availability not publicly disclosed
- ✗Pricing is above average ($299–$399/mo) compared to competitors
- ✗Compounded only — no brand-name options
- ✗Broader platform (metabolic, longevity, topical products)
Our Verdict
Both Actin and Vyora Wellness score equally well overall — the right choice depends on your priorities. Choose Actin if you want affordable compounded semaglutide with B12 enhancement, or Vyora Wellness if patients wanting coaching-inclusive compounded GLP-1 programs matters most to you.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.