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Actin vs Vaylen

An in-depth comparison of two leading GLP-1 Providers

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7.0

Actin

Best for affordable compounded semaglutide with B12 enhancement
★★★3.5

Starting at $133/mo

Compounded SemaglutideB12 Enhanced
Visit Actin
7.6

Vaylen

Best for GLP-1-focused care with oral and injectable options across all 50 states
★★★3.8

Starting at $179/mo

Compounded SemaglutideCompounded TirzepatideOral GLP-1Ozempic
Visit Vaylen

Side-by-Side Comparison

FeatureActinVaylen
Overall Score7.0/107.6/10
Starting Price$133/mo$179/mo
Editorial Rating3.5 ★ /53.8 ★ /5
Features2 features7 features
States Available050
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

Actin

Pros

  • Semaglutide + B12 combination for added energy support
  • Transparent pricing — exact cost shown upfront with no hidden fees
  • Competitive starting price from $133

Cons

  • Semaglutide only — no tirzepatide or liraglutide
  • No visible LegitScript or PCAB accreditation
  • State availability not disclosed
  • Broader platform (hormones, sexual wellness, hair health)

Vaylen

Pros

  • Pure GLP-1 specialist — not a multi-category telehealth platform
  • All 50 states coverage with licensed clinicians
  • Both compounded and brand-name options (Ozempic, Wegovy, Zepbound)
  • Oral GLP-1 option (compounded dissolvable tablets) for needle-averse patients
  • LegitScript certified
  • Transparent pricing — no hidden costs, no insurance required
  • Continuous coaching and lab support included

Cons

  • Compounded semaglutide at $179/mo is mid-range (not the cheapest)
  • Brand-name options at near-retail pricing ($997–$1,350/mo)

Our Verdict

Winner: VaylenScore: 7.6/10

Vaylen edges out Actin with a higher overall score of 7.6/10 and is particularly strong for GLP-1-focused care with oral and injectable options across all 50 states. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.