Actin vs PlushCare
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
PlushCare
Best for readers who want a primary-care relationship with GLP-1 prescribing as one option, AND who read the class-action disclosure and verify the cancellation flow before subscribingStarting at $149/mo
Side-by-Side Comparison
| Feature | Actin | PlushCare |
|---|---|---|
| Overall Score | 7.0/10 | 7.0/10 |
| Starting Price | ✓$133/mo | $149/mo |
| Editorial Rating | 3.5 ★ /5 | 3.5 ★ /5 |
| Features | 2 features | ✓7 features |
| States Available | 0 | ✓50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
PlushCare
Pros
- ✓All 50 states per the homepage
- ✓Appointments with US board-certified physicians (not nurse practitioners only)
- ✓Operates as virtual primary care, so the same provider can write GLP-1 prescriptions alongside other primary-care needs
- ✓Owned by Transcarent (post-Accolade-acquisition), a venture-backed health platform with named corporate parent
Cons
- ✗ACTIVE LITIGATION: California class action alleging deceptive subscription enrollment and unauthorized post-cancellation charges on the $19.99/month membership. Material disclosure for any reader signing up.
- ✗GLP-1 prescribing is clinician-discretionary at the visit level — not a guaranteed offering at intake
- ✗BBB rating reflects an ongoing pattern of complaints around the membership cancellation flow
Our Verdict
Both Actin and PlushCare score equally well overall — the right choice depends on your priorities. Choose Actin if you want affordable compounded semaglutide with B12 enhancement, or PlushCare if readers who want a primary-care relationship with GLP-1 prescribing as one option, AND who read the class-action disclosure and verify the cancellation flow before subscribing matters most to you.
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