Actin vs Novi
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
Novi
Best for transparent all-in compounded GLP-1 pricingStarting at $174/mo
Side-by-Side Comparison
| Feature | Actin | Novi |
|---|---|---|
| Overall Score | 7.0/10 | ✓8.6/10 |
| Starting Price | ✓$133/mo | $174/mo |
| Editorial Rating | 3.5 ★ /5 | ✓4.3 ★ /5 |
| Features | 2 features | ✓5 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
Novi
Pros
- ✓Transparent all-in monthly pricing — medication, clinician support, and shipping bundled with no hidden fees or membership add-ons
- ✓Both compounded semaglutide and tirzepatide available
- ✓Unlimited clinician messaging included at no extra cost
- ✓Free 2-day shipping on every refill
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
- ✗3-month minimum commitment is non-refundable per Terms of Service unless a clinician deems treatment medically inappropriate
- ✗State availability and pharmacy partners not publicly listed — patients learn during intake which states and pharmacies serve them
Our Verdict
Novi edges out Actin with a higher overall score of 8.6/10 and is particularly strong for transparent all-in compounded GLP-1 pricing. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.