Actin vs Navio MD
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
Navio MD
Best for compounded tirzepatide with brand-name fallback across 48 statesStarting at $247/mo
Side-by-Side Comparison
| Feature | Actin | Navio MD |
|---|---|---|
| Overall Score | 7.0/10 | ✓7.4/10 |
| Starting Price | ✓$133/mo | $247/mo |
| Editorial Rating | 3.5 ★ /5 | ✓3.7 ★ /5 |
| Features | 2 features | ✓5 features |
| States Available | 0 | ✓48 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
Navio MD
Pros
- ✓LegitScript verified with board-certified providers and US-licensed pharmacies
- ✓Same price at every dose — no price escalation
- ✓Both compounded and brand-name options
- ✓48-state coverage
- ✓Hours 9am–10pm EST Mon–Sun
Cons
- ✗Not available in Alabama and Mississippi
- ✗Compounded option is tirzepatide only — no compounded semaglutide listed
- ✗Brand-name at near-retail pricing ($1,199–$1,249/mo)
- ✗Also offers women's HRT (broader platform)
Our Verdict
Navio MD edges out Actin with a higher overall score of 7.4/10 and is particularly strong for compounded tirzepatide with brand-name fallback across 48 states. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.
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