Actin vs Effecty
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
Effecty
Best for nationwide compounded semaglutide with brand-name fallbackStarting at $160/mo
Side-by-Side Comparison
| Feature | Actin | Effecty |
|---|---|---|
| Overall Score | 7.0/10 | ✓7.5/10 |
| Starting Price | ✓$133/mo | $160/mo |
| Editorial Rating | 3.5 ★ /5 | ✓3.8 ★ /5 |
| Features | 2 features | ✓6 features |
| States Available | 0 | ✓50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
Effecty
Pros
- ✓Both compounded and brand-name GLP-1 options (Ozempic, Wegovy, Zepbound, Mounjaro)
- ✓LegitScript certified
- ✓Ships to all states nationwide
- ✓No membership fees — transparent pricing
- ✓Compounded semaglutide from $160/mo on annual plan
Cons
- ✗Compounded option is semaglutide only — no compounded tirzepatide
- ✗Brand-name options at full retail price ($1,300–$1,600/mo)
- ✗Also offers longevity and women's HRT (broader platform)
Our Verdict
Effecty edges out Actin with a higher overall score of 7.5/10 and is particularly strong for nationwide compounded semaglutide with brand-name fallback. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.