Actin vs Arc-1
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
Arc-1
Best for patients seeking per-dose compounded GLP-1 without subscriptionsStarting at $250/mo
Side-by-Side Comparison
| Feature | Actin | Arc-1 |
|---|---|---|
| Overall Score | ✓7.0/10 | 6.4/10 |
| Starting Price | ✓$133/mo | $250/mo |
| Editorial Rating | ✓3.5 ★ /5 | 3.2 ★ /5 |
| Features | 2 features | 2 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
Arc-1
Pros
- ✓Both compounded semaglutide and tirzepatide available
- ✓Per-dose purchasing — no subscription or membership required
- ✓25% off + free shipping promotional offer
- ✓Broader longevity formulary (Rapamycin, NAD+, Sermorelin)
Cons
- ✗No visible LegitScript or PCAB accreditation
- ✗No legal entity name or address disclosed
- ✗State availability not disclosed
- ✗Pricing is per-dose not monthly — higher doses are very expensive ($1,085-$1,585 for semaglutide 1.75-2.5mg)
- ✗No named clinicians or pharmacy partners
Our Verdict
Actin edges out Arc-1 with a higher overall score of 7.0/10 and is particularly strong for affordable compounded semaglutide with B12 enhancement. Arc-1 remains a solid alternative, especially if you're looking for patients seeking per-dose compounded GLP-1 without subscriptions.
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