✓Expert Reviewed📅Updated April 2026🔒Independently Researched
ReflexMD vs Sesame
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
6.9
ReflexMD
Best for comprehensive concierge careStarting at $297/mo
CompoundedSemaglutideTirzepatide
Visit ReflexMD →6.9
Sesame
Best for mainstream telehealth GLP-1 accessStarting at $199/mo
CompoundedSemaglutideTirzepatide
Visit Sesame →Side-by-Side Comparison
| Feature | ReflexMD | Sesame |
|---|---|---|
| Overall Score | 6.9/10 | 6.9/10 |
| Starting Price | $297/mo | ✓$199/mo |
| Customer Rating | — | — |
| Features | 3 features | 3 features |
| States Available | 50 | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
ReflexMD
Pros
- ✓Both semaglutide and tirzepatide available
- ✓Compounded GLP-1 access
Cons
- ✗Premium pricing relative to market
Sesame
Pros
- ✓Both semaglutide and tirzepatide available
- ✓Compounded GLP-1 access
Cons
- ✗Limited public information on program details
Our Verdict
Both ReflexMD and Sesame score equally well overall — the right choice depends on your priorities. Choose ReflexMD if you want comprehensive concierge care, or Sesame if mainstream telehealth GLP-1 access matters most to you.