Expert Reviewed📅Updated April 2026🔒Independently Researched

Piper vs ReflexMD

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.6

Piper

Best for mainstream telehealth GLP-1 access

Starting at $135/mo

CompoundedSemaglutideTirzepatide
Visit Piper
6.9

ReflexMD

Best for comprehensive concierge care

Starting at $297/mo

CompoundedSemaglutideTirzepatide
Visit ReflexMD

Side-by-Side Comparison

FeaturePiperReflexMD
Overall Score7.6/106.9/10
Starting Price$135/mo$297/mo
Customer Rating
Features3 features3 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

Piper

Pros

  • Aggressively low monthly pricing
  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Cons

  • Limited public information on program details

ReflexMD

Pros

  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Cons

  • Premium pricing relative to market

Our Verdict

Winner: PiperScore: 7.6/10

Piper edges out ReflexMD with a higher overall score of 7.6/10 and is particularly strong for mainstream telehealth GLP-1 access. ReflexMD remains a solid alternative, especially if you're looking for comprehensive concierge care.