Expert Reviewed📅Updated April 2026🔒Independently Researched

LifeMD vs Piper

An in-depth comparison of two leading GLP-1 Providers

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7.1

LifeMD

Best for non-GLP-1 weight management
Not Currently Offered
Visit LifeMD
7.6

Piper

Best for mainstream telehealth GLP-1 access

Starting at $135/mo

CompoundedSemaglutideTirzepatide
Visit Piper

Side-by-Side Comparison

FeatureLifeMDPiper
Overall Score7.1/107.6/10
Starting Price$135/mo
Customer Rating
Features1 features3 features
States Available5050
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

LifeMD

Pros

  • Telehealth convenience
  • Physician-supervised program

Cons

  • GLP-1 medications not currently offered

Piper

Pros

  • Aggressively low monthly pricing
  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Cons

  • Limited public information on program details

Our Verdict

Winner: PiperScore: 7.6/10

Piper edges out LifeMD with a higher overall score of 7.6/10 and is particularly strong for mainstream telehealth GLP-1 access. LifeMD remains a solid alternative, especially if you're looking for non-GLP-1 weight management.